Project Description

Author: Hasan et al.


Acute poisoning is a public health concern causing a significant amount of morbidity and mortality in Bangladesh. To analyze the presentation and outcomes of acute poisoning patients in Bangladesh since 1971. MEDLINE/PubMed, Banglajol, SciELO network and Google Scholar were searched for publications from 1971 to April 2020. A manual search for additional relevant studies using references from retrieved articles was also performed. Only studies that reported acute poisoning were included except snake bites. The screened articles and data were extracted for baseline characteristics, types of poisoning, and for relevant clinical end points. A total of 21 studies were included comprising 3,331 participants. The highest prevalence of acute poisoning for individuals under the age of 30 years in adults and in children aged 1-2 years, with higher frequency among males. Organophosphate compounds (OPCs) and household cleaning agents were the predominant agents. Suicidal intention was commonly reported, followed by accidental and criminal or homicidal poisoning. Family disharmony or marital problems were frequently identified as underlying factors in acute poisoning events. Toxic agents were primarily obtained from a dispensary or previously purchased for agricultural use. The majority of patients purchased poisoning agent themselves but some ingested leftover samples. The average time to seek medical assistance after poisoning ranged from 30 min to 24 hours. The overall prevalence of pre-hospital treatment ranged from 36.7-77.94%, and primarily consisted in induction of vomiting by different substances. Duration of hospital stay and case fatality rate ranged from <1 day-14 days and 0–24.9%, respectively. Acute poisoning is more common in children and in younger in Bangladesh. OPCs and household cleaning substances are common, particularly in suicide attempts. Time to seek emergency medical assistance, hospital stay duration, and case fatality rates were highly variable and depended on the type of poison ingested.

Status: Completed

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