Project Description

Author: Hassan et al.

Summary:

The objective of this study was to assess the pattern of iron indices in non-dialysis CKD patients with anemia.

This study was a cross-sectional study conducted on patients with non-dialysis CKD and concurrent anemia. The study was conducted in the Department of Medicine at Rangpur Medical College for a period of six months. A total of 50 patients were taken through purposive sampling. Staging of CKD and severity of anemia were done according to the criteria developed by the National Kidney Foundation and World Health Organization accordingly. For data collection a pre-structured questionnaire was used. Statistical analysis was performed using SPSS V-25.

Mean age of the patients was 47 years, with slight male predominance. One-fifth of the studied patients had overall low iron indices. Low levels of ferritin and transferrin saturation were observed in 18% and 20% of the patients accordingly. Mean serum ferritin, iron, total iron-binding capacity (TIBC) and transferrin saturation (TSAT) were 244.10±157.73 ng/ml, 80.80±34.40µg/dl, 266.84±71.62µg/dl, and 30.54±10.36%. Serum ferritin & TIBC tended to increase and iron and TSAT tended to decrease with the progression of CKD. But no statistical significance was noted (p>.05). An increased ferritin level in mild to moderate anemia was observed while a decreased ferritin level was noted in severe anemia. TSAT showed downward trends with anemia severity.

Conclusion: Changes in iron indices occur in non-dialysis CKD patients with anemia and vary with the severity of CKD.

Status: Ongoing

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