Project Description

Author: Ashab et al.


Ischemic heart disease is the most prevalent non-communicable disease in the world. Cervical spondylosis (CS) patients presenting with typical chest pain may have underlying myocardial ischemia (MI) which often remain unexplored. This study aimed to investigate the prevalence of inducible myocardial ischemia among the patients with cervical spondylosis and typical chest pain.

Method: We included a total of 54 adult CS patients presenting with typical chest pain for this cross-sectional analytical study. All of them underwent dobutamine stress echocardiography using standard protocol. Informed written consent was ensured before participation. Ethical measures were taken in compliance with the declaration of Helsinki.

Result: The average age of all participants was 44.8±7.6 years (SD) with a higher proportion of female (64.8%). Of all, 13 (24.1%) patients had inducible myocardial ischemia on dobutamine stress echocardiography. ECG findings suggestive of MI was noted in 7 out of 13 patients (53.8%) with inducible myocardial ischemia and in 1 out of 41 patients (2.4%) without inducible myocardial ischemia. Out of 13 patients with myocardial ischemia 7 (53.8%) had an abnormal ECG and out of 41 patients without inducible ischemia 1 (2.4%) had abnormal ECG. Single vessel involvement was the predominant finding (92.3%), and, respectively, 53.8% and 38.5% had involvement of left anterior descending and right coronary artery territory. Age (Adjusted OR[AOR] 1.17, 95% Confidence Interval [CI] 1.01 – 1.35), male sex (AOR 20.75, 95% CI 1.11 – 353.19), and diabetes mellitus (AOR 83.73, 95% 1.72 – 4067.56) were the independent predictors of myocardial ischemia in these patient groups.

Conclusion: Nearly one- quarter cervical spondylosis patients presenting with typical chest pain had underlying inducible myocardial ischemia. Further large case-control studies are recommended to determine the extent of the disease and predictors.

Keywords: Myocardial Ischemia, Cervical Spondylosis, Cervical Angina, Non-cardiac Chest pain, Inducible Myocardial Ischemia

Status: Ongoing

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