Epidemiological Investigation of the 2019 Dengue Outbreak in Dhaka, Bangladesh

Author: Yesmin et al. Summary: Bangladesh experienced its largest dengue epidemic in 2019. Our objective was to investigate the epidemiological, clinical, and laboratory characteristics of the hospital-admitted dengue patients during this epidemic. This cross-sectional study was conducted among 369 adult dengue patients admitted to two tertiary care hospitals in Dhaka, Bangladesh, from June to September 2019. The disease severity was determined according to the WHO’s 2009 classification. The average age of the patients was 33.3 (SD 14) years with a predominance of men. Almost 10% developed severe dengue (plasma leakage 67%, clinical bleeding 25%, and organ involvement 25%). Fever, headache,

By |December 22nd, 2023|Categories: |Tags: |0 Comments

Brolucizumab in the management of Diabetic Macular Edema (DME) and Age-Related Macular Degeneration (AMD): An In-depth evaluation through a Case Series.

Author: Moniruzzaman et al. Summary: Anti-VEGF therapies have emerged as the standard treatment for age-related macular degeneration (AMD) and diabetic macular edema (DME), leading to a significant reduction in vision loss. However, the frequent injections required for these therapies impose a burden on patients, caregivers, and the healthcare system. Additionally, maintaining long-term visual improvement can be challenging. To address these issues, Brolucizumab, an intravitreal anti-VEGF therapy, has been approved for the treatment of AMD and DME. It offers a longer duration of action and a drying effect, potentially reducing the need for frequent injections and providing an effective treatment option.

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Real world effectiveness of Brolucizumab for managing retinal diseases (Diabetic Macular Edema & Age related Macular Degeneration) focusing fluid control for both naive & uncontrolled patients

Author: Abdur-rahman et al. Summary: Diabetic Macular Edema (DME) and Age-Related Macular Degeneration (AMD) are two significant causes of vision impairment and central vision loss that impose an increasingly high burden on both patients and healthcare systems worldwide. The preferred treatment for DME and AMD patients is the use of anti-vascular endothelial growth factor (VEGF) agents. These agents play a crucial role in triggering angiogenesis, enhancing vascular permeability, disrupting the blood retinal barrier, and inducing inflammatory reactions.1 At present there are three approved VEGF-agents for treatment of AMD and DME: Ranibiziumab, Aflibercept and Brolucizumab. Extensive evidence has demonstrated that the

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Rheumatoid Hand-like Deformities and Aortic Valve Disease in A 13-year-old Girl with Familial Hypercholesterolemia

Author: Rahman et al. Summary: Familial Hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated serum low-density lipoprotein cholesterol (LDL-C) levels, tendon xanthomas, and an increased risk of atherosclerotic heart disease. Diagnosing Familial Hypercholesterolemia (FH) at an early age is crucial due to its potential to lead to severe cardiovascular complications, including heart failure, joint deformities and strokes. Early detection allows for timely intervention, such as lifestyle modifications and pharmacological treatments, which can significantly reduce these risks. Case Presentations: In this case report, we present a case of FH in a 13-year-old girl residing in Faridpur, Bangladesh. The patient

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Acute Hypothermia in a Patient with COVID-19: A Case Report and Summary of the Evidence

Author: Jyoti et al. Summary: SARS-COV-2 is a novel coronavirus that causes serious physical and mental complications among people across the globe. SARS-COV-2 has many presenting signs, wherein fever, coughing, and myalgia are the most typical symptoms, according to meta-analyses. However, having the enormous ability of mutation, the virus is continuously changing its genetic pattern and elucidating newer and rarer manifestations. Here, we report a case of adult COVID-19 along with features of hypothermia which is relatively rare and has future implications in clinical perspective. The patient presented with hypothermia and indicative symptoms of COVID-19 during admission. Comorbidities were assessed

By |December 22nd, 2023|Categories: |Tags: |0 Comments

Optimizing Survival in Russell’s Viper Bite Cases in Low-Resource Setting: Insight from two Case reports.

Author: Sharif et al. Summary: Introduction: Snakebite envenomation poses a significant health risk, particularly in low-resource settings where access to proper treatment is limited. Case presentation: This study reports two cases of Russell's viper bites in rural Bangladesh, involving 48 and 35-year-old males, respectively, and highlights the difficulties in providing adequate medical care and in treating any complications that may arise. Both cases involved delayed access to healthcare, initial visit to traditional healers, and the development of severe complications such as coagulopathy, renal failure. After the intervention both cases survived which is scarce in low resource settings. The cases underscore

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A case report on incidentally detected pulmonary sclerosing pneumocytoma (PSP): A diagnostic challenge

Author: Mursalin et al. Summary: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign lung tumor that typically doesn't show symptoms, but can cause breathing difficulties if it grows large. These tumors are often found accidentally because they grow slowly, don't cause symptoms, have distinct features on imaging, and imaging techniques are used more frequently. Despite being non-cancerous, PSP can resemble malignant tumors in imaging and tissue examination, potentially leading to incorrect diagnosis and unnecessary surgery. This case report aims to detail a case where PSP was incidentally discovered during a medical assessment for a fibroadenoma in the chest region. Keywords:

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Optimizing Survival in Russell’s Viper Bite Cases in Low-Resource Setting: Insight from two Case reports

Author: sharif et al. Summary Snakebite envenomation poses a significant health risk, particularly in low-resource settings where access to proper treatment is limited. This study reports two cases of Russell's viper bites in rural Bangladesh, involving 48 and 35-year-old males, respectively, and highlights the difficulties in providing adequate medical care and in treating any complications that may arise. Both cases involved delayed access to healthcare, initial visit to traditional healers, and the development of severe complications such as coagulopathy, renal failure. After the intervention both cases survived which is scarce in low resource settings. The cases underscore the importance of

By |December 22nd, 2023|Categories: |Tags: |0 Comments
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